Finally Delivering An Effective Therapy For Cystic Fibrosis
Although cystic fibrosis has long been used as an example of where gene therapy could eventually improve clinical outcomes, it turns out that more conventional chemistry can still play a meaningful role. Between Kalydeco and two clinical CTFR ��orrectors�� Vertex has made a major step forward in the treatment of a disease that while not as lethal as it once was (at least in the U.S. and EU), is still a very serious and difficult to manage chronic illness.
Top 5 Railroad Stocks To Watch Right Now: Lear Corp (LEA)
Lear Corporation, incorporated in 1987, is a tier 1 supplier to the global automotive industry. The Company supplies its products to automotive manufacturers with automotive seat systems and related components, as well as electrical distribution systems and related components. The Company has two segments: seating and electrical power management systems (EPMS). The seating segment includes seat systems and related components, such as seat frames, recliner mechanisms, seat tracks, seat trim covers, headrests and seat foam. The EPMS segment includes electrical distribution systems for traditional powertrain vehicles, as well as for hybrid and electric vehicles. As of December 31, 2011, it had 20 joint ventures located throughout Asia, as well as five in North America, two in Europe and Africa and one with operations in all three regions.
Seating Segment
The Seating Segment consists of the design, manufacture, assembly and supply of vehicle seating requirements. It produces seat systems for automobiles and light trucks that are assembled and ready for installation. In all cases, seat systems are designed and engineered for specific vehicle models or platforms. It has developed modular seat architectures for both front and rear seats. It produces components for seat assemblies, such as seat frames, recliner mechanisms, seat tracks, seat trim covers, headrests and seat foam.
The Company competes with Johnson Controls, Inc., Faurecia S.A., Toyota Boshoku Corporation, TS Tech Co., Ltd. and Magna International Inc.
EPMS Segment
The EPMS segment consists of the design, manufacture, assembly and supply of electrical distribution systems and components for traditional powertrain vehicles, as well as for hybrid and electric vehicles. Electrical distribution systems are comprised primarily of wire harness assemblies, terminals and connectors and control modules, including junction boxes and fuse boxes. Wire harness assemblies consist of a collection! of wiring and terminals and connectors that connect all of the various electrical and electronic devices within the vehicle to each other and/or to a power source.
Electrical distribution systems are networks of wiring and associated control devices that route electrical signals and manage electrical power within a vehicle. Wire harness assemblies consist of raw, coiled wire, which is cut to length and terminated. Individual circuits are assembled together on a jig or table, inserted into connectors and wrapped or taped to form wire harness assemblies.
Wireless products send and receive signals using radio frequency technology. The Company�� wireless systems include passive entry systems and dual range/dual function remote keyless entry systems. Passive entry systems allow the vehicle operator to unlock the door without using a physically activating a remote keyless fob. Dual range/dual function remote keyless entry systems allow a single transmitter to perform multiple functions. The lighting control module integrates electronic control logic and diagnostics with the headlamp switch. Entertainment products include radio amplifiers, sound systems, in-vehicle television tuner modules and floor-, seat- or center console-mounted Media Console with a flip-up screen that provides digital video disc (DVD) and video game viewing for back-seat passengers.
The Company competes with Yazaki Corporation, Sumitomo Corporation, Delphi Automotive PLC, Leoni AG and Furukawa Electric Co., Ltd., TE Connectivity, Ltd., Continental AG, Hella, Inc., Robert Bosch LLC, Magna E-Car Systems GmbH & Co OG and Hitachi, Ltd.
Advisors' Opinion:- [By Ben Levisohn]
Shares of Lear Corp. (LEA) have returned 66% including reinvested dividends. Has that run made Lear’s stock expensive?
Agence France-Presse/Getty ImagesThat depends on whom you ask. For Deutsche Bank’s Rod Lache�it has, despite the solid earnings numbers that have helped drive Lear higher. He writes:
Lear�� Q3 EPS of $1.45 was meaningfully better than our $1.26 est. and cons. of $1.33. Looking at LEA�� divisions, the Seating margin came in slightly better than we projected, at 5.4% vs. our 5.2% est. but still down vs. 6.1% in Q3��2. EPMS drove most of the upside with an op. margin of 10.9% vs. 7.5% in 3Q12 (including a 50 bp nonrecurring positive). LEA�� overall corp. op. margin came in at 5.4% vs. our 4.7% est. While we were impressed by Lear�� Q3, we are lowering our recommendation to Hold based on valuation.
Not so fast, says Citigroup’s�Itay Michaeli. He writes:�
In our view, Lear�� valuation remains appealing for two core reasons: (1) Lear sports structurally�lower capex/sales vs. peers (< 3% vs. ~4+% for peers). That means that for a given EBITDA multiple, Lear will generate higher unlevered FCF than its peers, all else equal. Our 6.0x ��4E EBITDA target multiple = ~8% unlevered FCF yield, including restructuring. That Lear�� revenue is outpacing the industry while margins are expanding is evidence that capex is appropriately sized. We estimate Lear�� ��4 unlevered FCF yield is comfortably above peer average; (2) Lear�� EPMS segment appears to have crossed the threshold to becoming a double-digit EBITDA margin earner with clear secular growth attributes. We think a 7.5x EBITDA multiple is appropriate based on public peers (Delphi (DLPH)) and past connector M&A.�
Shares of Lear have gained 0.2% to $77.32 at 2:24 p.m. on a day when most auto-part companies are not doing much of anything.�Delphi Automotive, the big loser, has dropped 1.1% to $57.39,�Johnson Controls�/li>
- [By Seth Jayson]
Lear (NYSE: LEA ) is expected to report Q1 earnings around April 25. Here's what Wall Street wants to see:
The 10-second takeaway
Comparing the upcoming quarter to the prior-year quarter, average analyst estimates predict Lear's revenues will grow 1.5% and EPS will decrease -19.6%. - [By Laura Brodbeck]
Earnings reports expected on Friday include:
Procter & Gamble Company (NYSE: PG) is expected to report first quarter EPS of $1.06 on revenue of $21.09 billion, compared to last year�� EPS of $1.06 on revenue of $20.74 billion. United Parcel Services (NYSE: UPS) is expected to report EPS of $1.15 on revenue of $13.60 billion, compared to last year�� EPS of $1.06 on revenue of $13.07 billion. Moody�� Corporation (NYSE: MCO) is expected to report third quarter EPS of $0.81 on revenue of $715.85 million, compared to last year�� EPS 0f $0.75 on revenue of $688.50 million billion. Lear Corporation (NYSE: LEA) is expected to report third quarter EPS of $1.33 on revenue of $3.84 billion, compared to last year�� EPS 0f $1.29 on revenue of $3.54 billion.Economics
10 Best Stocks For 2014: Pembina Pipeline Corp (PBA)
Pembina Pipeline Corporation (Pembina) is a Calgary-based company, engaged in providing transportation and midstream services. It owns and operates: pipelines that transport conventional and synthetic crude oil and natural gas liquids produced in western Canada; oil sands, heavy oil and diluent pipelines; gas gathering and processing facilities; and, an oil and natural gas liquids infrastructure and logistics business. It has facilities located in western Canada and in natural gas liquids markets in eastern Canada and the United States. Pembina also offers a spectrum of midstream and marketing services. Pembina�� Midstream business is organized into two segments: crude oil and NGL. The crude oil segment represents the Company�� midstream operations. The NGL segment includes two operating systems: Redwater West and Empress East. Pembina's Conventional Pipelines business consists of a pipeline network, located 7,850 kilometers, that extends across much of Alberta and British Columbia. Advisors' Opinion:- [By Rich Duprey]
Midstream operator Pembina Pipeline (NYSE: PBA ) announced yesterday its monthly dividend for July, of $0.135 per share, which is designated an "eligible dividend" for Canadian income tax purposes. For non-resident shareholders, Pembina's dividends are considered "qualified dividends," subject to Canada's withholding tax.
10 Best Stocks For 2014: Mead Johnson Nutrition Company (MJN)
Mead Johnson Nutrition Company manufactures, distributes, and sells infant formulas, children?s nutritional products, and other nutritional products in Asia, Europe, Latin America, and North America. Its infant formula products include formulas for routine feeding; solutions formulas for mild intolerance and specialty formula products, including formulas for severe intolerance; formulas for premature and low birth weight infants; and medical nutrition products. The company also offers products for infants with milk protein allergy, gas/fussiness, lactose intolerance, anti-regurgitation, severe protein sensitivity, multiple food allergies, fat malabsorption, and premature infants, as well as soy formula. Its children?s nutrition products comprise nutritious powdered milk for picky eaters, nutritious powdered milk, and nutritious milk modifier. The company also offers a range of other products, including pre-natal and post-natal nutritional supplements for expectant and nurs ing mothers. Mead Johnson Nutrition Company markets its products under the Enfamil, Enfalac, Enfapro, Nutramigen, Pregestimil, Enfacare, Enfagrow, EnfaSchool, Enfakid, Sustagen KID, Lactum, Alacta, ChocoMilk, Cal-C-Tose, Expecta LIPIL, and EnfaMama names. It sells its products to retail channels, including mass merchandisers, club stores, grocery stores, drug stores, and convenience stores. The company was founded in 1905 and is headquartered in Glenview, Illinois. Mead Johnson Nutrition Company (NYSE: MJN), formerly a subsidiary of Bristol-Myers Squibb Co., completed its initial public offering in February 2009.
Advisors' Opinion:- [By Jim Jubak]
Six milk powder producers, charged by China's National Development and Reform Commission with price fixing, have pled guilty and will be fined 669 million yuan ($109 million.) The companies—Mead Johnson Nutrition (MJN), Danone (DANOY) subsidiary Dumex, Abbott Laboratories (ABT), Fonterra Cooperative Group (FSF:AU), FrieslandCampina, and Biostime International Holdings—admitted they set minimum prices for distributors in order to keep prices high. Many of the companies had earlier cut the prices they charge in China—Fonterra had cut the price of its Anmun brand of baby formula 9%, Abbott Laboratories had reduced prices by as much as 12%, and Mead Johnson had lowered prices by 7% to 15%. This is, CaixinOnline reports, the harshest penalty handed out under China's five-year-old anti-monopoly law. The announcement of the fine, hard on the heels of a ban by China on all imports of whey protein products from Fonterra—after regulators found a batch of whey from a Fonterra plant in New Zealand contaminated with botulism—makes it clear that something big is going on here.
- [By Michael Flannelly]
On Tuesday, JP Morgan analysts upgraded children’s nutrition company Mead Johnson Nutrition (MJN), as they believe the company’s top line growth should be valued more highly than the possible cost headwinds and further Chinese regulations.
The analysts upgraded MJN from “Neutral” to “Overweight” and see shares reaching $88. This price target suggests a 16% upside to the stock’s Monday closing price of $76.11.
Mead Johnson Nutrition shares were up 85 cents, or 1.12%, during morning trading on Tuesday. The stock is up 16.71% year-to-date.
10 Best Stocks For 2014: PowerShares International Dividend Achievers Portfolio (PID)
PowerShares International Dividend Achievers Portfolio (the Fund) seeks to replicate, before fees and expenses, the International Dividend Achievers Index (the Index). The Fund invests in sectors, including financials, utilities, consumer staples, commercial banks, insurance, utilities and information technology. PowerShares Capital Management LLC is the adviser of the Fund.
The Index seeks to identify an international group of American Depository Receipts that have qualified as International Dividend Achievers. The Index is designed to track the performance of dividend paying American Depository Receipts and non-United States common or ordinary stocks trading on the NYSE, NADDAQ or AMEX.
Advisors' Opinion:- [By Carlton Delfeld]
Second, add to the mix, one of my long-time favorite ETFs, the PowerShares International Dividend Achievers (PID).
To get into this exclusive basket, companies have to have a record of increasing dividends for five consecutive years. The United Kingdom and Canada make up 50% of its holdings with the US at only 6%.
- [By Editor , DividendChannel.com]
According to the ETF Finder at ETF Channel, Enbridge stock is an underlying holding representing 1.97% of the Powershares International Dividend Achievers ETF (PID), which holds $20,709,837 worth of ENB shares.
10 Best Stocks For 2014: UC Resources Ltd (UC&C)
UC Resources Ltd. is an exploration-stage company. The Company is engaged principally in the acquisition, exploration and development of mineral properties in Mexico. The Company focuses on silver and gold exploration and production in Mexico. Its mineral properties include Copalquin property (Copalquin Project) and La Yesca. Its Copalquin is located in the northwestern state corner of Durango State, in Mexico. La Yesca is 100% owned by the Company�� subsidiary, Minera Silver Creeck. The La Yesca milling project is located near the town of La Yesca in Nayarit, Mexico, approximately 100 kilometers northwest of Guadalajara City. In the La Yesca district there are at least 16 known gold and silver mineral discoveries. The Mar project consists of a 100 hectare mining exploitation concession. On September 6, 2012, the Company discovered another previously unknown existing mine prospect on the La Yesca property just North of La Leona Mine. Advisors' Opinion:- [By Victor Selva]
Polycom provides standards-based unified communications and collaboration (UC&C) solutions for voice and video collaboration. The company has three products and solutions categorized as follows: UC Platform, UC Group Systems and UC Personal Devices.
10 Best Stocks For 2014: G-III Apparel Group Ltd (GIII)
G-III Apparel Group, Ltd. (G-III) designs, manufactures and markets a range of apparel, including outerwear, dresses, sportswear, women�� suits and women�� performance wear, as well as luggage and women�� handbags, small leather goods and cold weather accessories. It operates in three segments: wholesale licensed products, wholesale non-licensed products and retail operations. The wholesale licensed products segment includes sales of products under brands licensed by it from third parties. The wholesale non-licensed products segment includes sales of products under its own brands and private label brands. The retail operations segment consists almost entirely of the operations of its Wilsons outlet stores. The Company sells its products under its own brands, which include Andrew Marc, Marc New York and Marc Moto, licensed brands and private retail labels. In August 2012, the Company acquired Vilebrequin, a provider of swimwear, accessories and resort-wear. Effective November 4, 2013, G-III Apparel Group Ltd acquired GH Bass & Co.
The Company provides apparel under recognized brands to a cross section of retailers, such as Macy��, Bloomingdale��, Nordstrom, Lord & Taylor, The Bon-Ton Stores, Dillards, JC Penney, Belk and Kohl��. As of January 31, 2012, the Company operated 139 retail stores, of which 135 are outlet stores operated under the Wilsons Leather name and four are outlet stores operated under its Andrew Marc brand. It has licenses to produce branded fashion apparel under the Calvin Klein, Kenneth Cole, Cole Haan, Guess?, Tommy Hilfiger, Levi��, Dockers, Jessica Simpson, Ellen Tracy, Kensie, Mac & Jac, Jones New York, Sean John and Nine West brands, among others. It also has sports licenses with the National Football League, National Basketball Association, Major League Baseball, National Hockey League, Touch by Alyssa Milano and over 100 United States colleges and universities. G-III sells outerwear, dresses and handbags under the Company�� own Andrew Marc, Marc ! New York and Marc Moto brands and has licensed these brands to select third parties in certain product categories. Its other owned brands include, among others, Jessica Howard, Eliza J, Black Rivet, G-III, G-III Sports by Carl Banks and Winlit.
The Company works with a group of retailers, such as JC Penney, Kohl�� and Express in developing private label product lines. G-III�� products are sold primarily to department, specialty and mass merchant retail stores in the United States. It sells to approximately 2,400 customers, ranging from national and regional chains to small specialty stores. It also distributes its products through its retail outlet stores. It also markets its products in Canada, Europe and the Far East.
G-III�� branded apparel also consists of both women�� and men�� products. The Andrew Marc line of women�� and men�� luxury apparel is sold to upscale department and specialty retail stores. The Marc New York line of women�� and men�� better priced outerwear is sold to upper tier stores. The Marc Moto line is a men�� denim lifestyle collection of sportswear and accessories. The Jessica Howard label is a moderate price dress line that sells to department stores, specialty stores and catalogs. Eliza J is a better dress line that sells to better department and specialty stores. The Black Rivet line of apparel consists of women�� and men�� outerwear. It sells men�� sports-related apparel under its G-III Sports by Carl Banks label.
Advisors' Opinion:- [By Amal Singh]
G-III Apparel (NASDAQ: GIII ) has a strong portfolio of 30 licensed brands, marketing apparel, outerwear, beachwear, luggage, women's handbags, small leather goods, and accessories, to name a few of its products. The company sells its apparel�offerings under popular brand names like Andrew Marc, Jessica Howard, Calvin Klein, Levi's, and Tommy Hilfiger. The company has also announced plans to revive the Starter Statin jacket franchise�. It is also looking at acquisitions and mergers to grow its business moving forward�.
- [By Seth Jayson]
G-III Apparel Group (Nasdaq: GIII ) reported earnings on June 3. Here are the numbers you need to know.
The 10-second takeaway
For the quarter ended April 30 (Q1), G-III Apparel Group beat expectations on revenues and beat expectations on earnings per share.
10 Best Stocks For 2014: United Therapeutics Corporation(UTHR)
United Therapeutics Corporation, a biotechnology company, engages in the development and commercialization of therapeutic products for patients with chronic and life-threatening diseases in the United States and internationally. It offers Remodulin, Tyvaso, and Adcirca for the treatment of pulmonary arterial hypertension (PAH). The company also develops Oral Treprostinil (UT-15C), a new drug application filed with the United States Food and Drug Administration for the treatment of PAH. Its development products under Phase III clinical trials include Oral Treprostinil (UT-15C) Combination Therapy for PAH; Ch14.18 monoclonal antibody (MAb) targeting Neuroblastoma; and Remodulin for the treatment of PAH in the United States, the United Kingdom, France, Germany, Italy, and Japan. The company?s development products under Phase I clinical trials comprise Beraprost-MR for PAH in North America, Europe, Mexico, South America, Egypt, India, South Africa, and Australia; 8H9 MAb targ eting Metastatic brain cancer; and IW001 for the treatment of Idiopathic pulmonary fibrosis and primary graft dysfunction. Its pre-clinical stage products consist of Glycobiology Antiviral Agents for viral infectious diseases; PLacental eXpanded cells targeting PAH; and pulmonary tissue replacement and remodeling products for the treatment of end-stage lung disease. The company serves pharmaceutical wholesalers through specialty pharmaceutical distributors and other distributors. United Therapeutics Corporation was founded in 1996 and is headquartered in Silver Spring, Maryland.
Advisors' Opinion:- [By John Udovich]
Yesterday, mid cap biotech stock�United Therapeutics Corporation (NASDAQ: UTHR) soared�30.36% after announced FDA approval of Orenitram as�an oral treatment for pulmonary arterial hypertension (PAH), meaning investors should take a closer look at the stock along with the performance of peers like the iShares NASDAQ Biotechnology Index ETF (NASDAQ: IBB) and the�SPDR S&P Biotech ETF (NYSEARCA: XBI).
- [By Monica Gerson]
United Therapeutics (NASDAQ: UTHR) shares reached a new 52-week high of $91.13. United Therapeutics' PEG ratio is 1.64.
DENTSPLY International (NASDAQ: XRAY) shares touched a new 52-week high of $47.65. DENTSPLY's trailing-twelve-month ROE is 15.95%.
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